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The exact distance between Des Moines, Iowa and St. Louis, Missouri is 273 miles (440 kilometers) by a straight line.

The distance from Des Moines, Iowa to St. Louis, Missouri by highways is about 319 miles and it is subject to a slight change depending on the chosen route. Travel time from Des Moines, Iowa to St. Louis, Missouri by car is about 5.3 hours and it also may vary depending on traffic. Upon planning a journey from Des Moines to St. Louis please take into consideration that travel times may vary or increase in case of traffic jams or bad weather. Please consider a public transport system when moving between Des Moines, Iowa and St. Louis, Missouri.

Where next? Distances to other cities from St. Louis, Missouri:

• Distance between St. Louis and Milwaukee, Wisconsin
• Distance between St. Louis and Rochester, New York
• Distance between St. Louis and Buffalo, New York
• Distance between St. Louis and Yonkers, New York
• Distance between St. Louis and Syracuse, New York
• Distance between St. Louis and Birmingham, Alabama
• Distance between St. Louis and Anchorage, Alaska
• Distance between St. Louis and Des Moines, Iowa
• Distance between St. Louis and Norfolk, Virginia
• Distance between St. Louis and Honolulu, Hawaii
• Distance between St. Louis and Athens, Georgia
• Distance between St. Louis and Augusta, Georgia
• Distance between St. Louis and Bakersfield, California
• Distance between St. Louis and Kansas City, Kansas
• Distance between St. Louis and Lexington, Kentucky
• Distance between St. Louis and Colorado Springs, Colorado
• Distance between St. Louis and Bridgeport, Connecticut
• Distance between St. Louis and Hartford, Connecticut
• Distance between St. Louis and New Orleans, Louisiana
• Distance between St. Louis and Minneapolis, Minnesota
• Distance between St. Louis and Jackson, Mississippi
• Distance between St. Louis and Cincinnati, Ohio
• Distance between St. Louis and Pittsburgh, Pennsylvania
• Distance between St. Louis and Providence, Rhode Island
• Distance between St. Louis and Miami, Florida
• Distance between St. Louis and Cleveland, Ohio
• Distance between St. Louis and Raleigh, North Carolina
• Distance between St. Louis and Tampa, Florida
• Distance between St. Louis and Salt Lake City, Utah
• Distance between St. Louis and Sioux Falls, South Dakota
• Distance between St. Louis and Manchester, New Hampshire
• Distance between St. Louis and Newark, New Jersey
• Distance between St. Louis and Omaha, Nebraska
• Distance between St. Louis and Billings, Montana
• Distance between St. Louis and Little Rock, Arkansas
• Distance between St. Louis and Wilmington, Delaware
• Distance between St. Louis and Charleston, West Virginia
• Distance between St. Louis and Burlington, Vermont
• Distance between St. Louis and Cheyenne, Wyoming
• Distance between St. Louis and Boise, Idaho
• Distance between St. Louis and Portland, Maine
• Distance between St. Louis and Fargo, North Dakota
• Distance between St. Louis and Columbia, South Carolina
• Distance between St. Louis and Virginia Beach, Virginia
• Distance between St. Louis and Montgomery, Alabama
• Distance between St. Louis and Dover, Delaware
• Distance between St. Louis and Tallahassee, Florida
• Distance between St. Louis and Springfield, Illinois
• Distance between St. Louis and Wichita, Kansas
• Distance between St. Louis and Topeka, Kansas